Pharmacology and Toxicology Department Highlights: April 2021
(April 1, 2021)
Publications
Predicting Drug Interactions with Human Equilibrative Nucleoside Transporters 1 and 2 Using Functional Knockout Cell Lines and Bayesian Modeling. Molecular Pharmacology. Vol. 99, Issue 2, 1 Feb 2021.
- Miller, S.
- Zhang, X.
- Hau, R.
- Jilek, J.
- Jennings, E.
- James J. GalligaN, PHD
- Foil, D.
- Zorn, K.
- Ekins, S.
- Stephen H. Wright, phd
- Nathan J. CherringtoN, PHD, ATS
Design and Comprehensive Characterization of Tetramethylpyrazine (TMP) for Targeted Lung Delivery as Inhalation Aerosols in Pulmonary Hypertension (PH): In Vitro Human Lung Cell Culture and In Vivo Efficacy. Antioxidants: Special Theme Issue: Antioxidants and Lung Diseases (2021) 10 (3) 427.
- Muralidharan, P.
- Acosta, M.F.
- Gomez, A.I.
- Grijalva, C.
- Tang, H.
- Yuan, J. X.-L.
- Heidi Mansour, PhD, RPh
Advanced therapeutic inhalation aerosols of a Nrf2 activator and RhoA/Rho kinase (ROCK) inhibitor for targeted pulmonary drug delivery in pulmonary hypertension: design, characterization, aerosolization, in vitro 2D/3D human lung cell cultures, and in vivo efficacy. Therapeutic Advances in Respiratory Disease (2021) 15:1-25. PMID: 33719747
- Acosta, M.F.
- Muralidharan, P.
- Grijalva, C.L.
- Abrahamson, M.D.
- Hayes, D. Jr.
- Fineman, J.R.
- Stephen Black, PHD
- Heidi Mansour, PhD, RPh
Boceprevir, calpain inhibitors II and XII, and GC-376 have broad-spectrum antiviral activity against coronavirues. bioRxiv. (2020) Nov 1. PMID: 33140049
- Hu, Y.
- Ma, C.
- Szeto, T.
- Hurst, B.
- Tarbet, B.
- JUN WAng, PHD
The in vitro antiviral activity of lactoferrin against common human coronaviruses and SARS-CoV-2 is mediated by targeting the heparan sulfate co-receptor. Emerging Microbes & Infections (2021), 10(1)
- Hu, Y.
- Meng, X.
- Zhang, F.
- Xiang, Y.
- JUN WanG, PHD
Dipyridamole, chloroquine, montelukast sodium, candesartan, oxytetracycline, and atazanavir are not SARS-CoV-2 main protease inhibitors. PNAS (2021) February 23 118 (8) e2024420118
- Ma, C.
- JUN WanG, PHD
Deuterium Oxide (D 2 O) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma. Cancers (2021) Feb 3; 13(4):605
- Jandova, J.
- Hua A.
- Fimbres J.
- Georg T Wondrak, PhD
FAM129B‐dependent activation of NRF2 promotes an invasive phenotype in BRAF mutant melanoma cells. Molecular Carcinogenesis (2021) Mar 8. PMID: 33684228
- Schmidlin, C.
- Tian, W.
- Dodson, M.
- Eli Chapman, PhD
- Donna D Zhang, PhD
Presentations
Discover Pharmacy BSPS Virtual Open House
- Dean Rick Schnellmann, PhD
- Jeannie K Lee, PharmD, BCPS, BCGP, FASHP
- Heidi Mansour, PhD, RPh
- Richard Vaillancourt, PhD
- TechLaunch Arizona (TLA) Celebrating Women's History Month
- Webinar : Research and Academic Bridges with Mexico – CONACyT Scholar Opportunities
- Being a Research Mentor to international students
- Drug discovery and pharmacology of antivirals targeting influenza virus, enterovirus D68, and SARS-CoV-2. Feb 4th, 2021 - Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy at the Purdue University
- SARS-CoV-2 antiviral drug discovery targeting the main protease and papain-like protease. Feb 27, 2021 - Chinese-American Bio/Pharmaceutical Society Webinar: COVID-19 small molecule drug discovery
- SARS-CoV-2 antiviral drug discovery targeting the main protease and papain-like protease. Feb 27, 2021 - 18th Hellenic Symposium on Medicinal Chemistry (Greece)
- SARS-CoV-2 antiviral drug discovery targeting the main protease and papain-like protease. Feb 24, 2021 - 6th Annual ABRC-Flinn Research Conference