Heidi Mansour, PhD, RPh

Associate Professor with Tenure, Pharmaceutical Sciences
Associate Professor, College of Medicine
Associate Member, UA NCI Comprehensive Cancer Center
Affiliate Faculty Member, UA Institute of the Environment
Associate Professor, UA BIO5 Research Institute
Track Director, Pharmaceutics and Pharmacokinetics
Director, PharmD/PhD Dual-Degree Joint Program

Heidi Mansour, PhD, RPh, associate professor with tenure, Department of Pharmacology and Toxicology, serves as associate professor, College of Medicine, and at the BIO5 Institute. Other appointments include track director, pharmaceutics and pharmacokinetics; associate member, NCI Comprehensive Cancer Center; affiliate faculty member, Institute of Environment and director, PharmD/PhD dual-degree joint program.

Editorial advisor to several journals, Mansour’s authored numerous peer-reviewed articles and book chapters. She serves on the drug-device discovery and development committee for the American Thoracic Society and annual faculty instructor, International Society of Aerosols in Medicine where she co-chaired the drug delivery: new devices and emerging therapies group.

Books

  • Inhalation Aerosols: Physical and Biological Basis for Therapy. Hickey, A. J. and Mansour, H.M. (Editors), Third Edition, Lung Biology in Health and Diseases Series, Executive Editor, Dr. Claude Lenfant, CRC Press/Taylor & Francis, London, United Kingdom. (2019) 418 pages. ISBN 9781138064799
  • Nanomedicine in Drug Delivery. Kumar, A., Mansour, H.M., Friedman, A., and Blough, E. (Editors), CRC Press/Taylor & Francis, London, United Kingdom. (2013) 469 pages. ISBN: 9781466506169

Patents/Inventions

Education: 

Post-Doctoral, Molecular Pharmaceutics, University of North Carolina, 2008
Post-Doctoral, Pharmaceutical Science, University of Wisconsin, 2004
PhD Major, Pharmaceutics/Drug Delivery, University of Wisconsin, 2003
PhD Minor, Advanced Physical and Interfacial Chemistry, University of Wisconsin, 1999
BS, Pharmacy, University of Wisconsin, 1996

Research Interests: 
  • Cystic fibrosis
  • Inhaled medical aerosols
  • Lung transplantation
  • Microparticulates/nanoparticulates
  • Pulmonary hypertension
  • Nanotechnology and nanomedicine
  • Lung surfactant and respiratory distress syndrome
  • Asthma
  • Infectious diseases
  • Acute lung injury
  • CNS and brain neurotherapeutics
  • Inhaled medical aerosols and inhaler devices
  • Advanced drug delivery systems
  • Drug-device combination products
  • In vitro USP/FDA performance testing
  • In vitro 2-D/3-D human cellular models for drug transport
  • In vivo animal models for PK/PD

Select Publications

2018

Mansour, H. M., "Inhaled medical aerosols by nebulizer delivery in pulmonary hypertension.", Pulm Circ, vol. 8, issue 4, pp. 2045894018809084, 2018 Oct-Dec. PMCID: PMC6201187 
Li, S. S., D. Tumin, K. A. Krone, D. Boyer, S. E. Kirkby, H. M. Mansour, and D. Hayes, "Risks associated with lung transplantation in cystic fibrosis patients.", Expert Rev Respir Med, vol. 12, issue 11, pp. 893-904, 2018 Nov.

2016

Hayes, D., S. M. Black, J. D. Tobias, B. T. Kopp, S. E. Kirkby, H. M. Mansour, and B. A. Whitson, "Influence of human leukocyte antigen mismatching on bronchiolitis obliterans syndrome in lung transplantation.", J Heart Lung Transplant, vol. 35, issue 2, pp. 186-94, 2016 Feb.
Muralidharan, P., D. Hayes, S. M. Black, and H. M. Mansour, "Microparticulate/Nanoparticulate Powders of a Novel Nrf2 Activator and an Aerosol Performance Enhancer for Pulmonary Delivery Targeting the Lung Nrf2/Keap-1 Pathway.", Mol Syst Des Eng, vol. 1, issue 1, pp. 48-65, 2016. PMCID: PMC5072457  PMID: 27774309
Meenach, S. A., A. N. Tsoras, R. C. McGarry, H. M. Mansour, Z. J Hilt, and K. W. Anderson, "Development of three-dimensional lung multicellular spheroids in air- and liquid-interface culture for the evaluation of anticancer therapeutics.", Int J Oncol, vol. 48, issue 4, pp. 1701-9, 2016 Apr. PMCID: PMC4777598  PMID: 26846376
de la Vega, M. Rojo, M. Dodson, C. Gross, H. Mansour, C. R Lantz, E. Chapman, T. Wang, S. M. Black, J. G. N. Garcia, and D. D. Zhang, "Role of Nrf2 and Autophagy in Acute Lung Injury.", Curr Pharmacol Rep, vol. 2, issue 2, pp. 91-101, 2016 04. PMCID: PMC4905711  PMID: 27313980
Hayes, D., D. Tumin, A. R. Yates, H. M. Mansour, K. K. Nicol, J. D. Tobias, and A. F. Palmer, "Transfusion with packed red blood cells while awaiting lung transplantation is associated with reduced survival after lung transplantation.", Clin Transplant, vol. 30, issue 12, pp. 1545-1551, 2016 Dec.
Hayes, D., P. I. McConnell, A. R. Yates, J. D. Tobias, M. Galantowicz, H. M. Mansour, and D. Tumin, "Induction immunosuppression for combined heart-lung transplantation.", Clin Transplant, vol. 30, issue 10, pp. 1332-1339, 2016 Oct.
Hayes, D., B. T. Kopp, S. E. Kirkby, S. D. Reynolds, H. M. Mansour, J. D. Tobias, and D. Tumin, "Impact of Donor Arterial Partial Pressure of Oxygen on Outcomes After Lung Transplantation in Adult Cystic Fibrosis Recipients.", Lung, vol. 194, issue 4, pp. 547-53, 2016 Aug.
Hayes, D., B. R. Younger, H. M. Mansour, and H. Strawbridge, "Precordial Catch Syndrome in Elite Swimmers With Asthma.", Pediatr Emerg Care, vol. 32, issue 2, pp. 104-6, 2016 Feb.