Dr. Mansour is an associate professor with tenure. She teaches in the BS Pharmaceutical Sciences undergraduate program, the PharmD Professional program and in the Pharmaceutics and Pharmacokinetics track of the graduate program.
Research in the Mansour lab focuses on the fundamental and applied aspects of surface and interfacial chemistry, nanotechnology, and particle engineering technologies in the design and optimization of advanced drug delivery systems. Multifunctional polymeric phospholipid (lipopolymeric) self-assemblies are optimized for targeted drug delivery, nanomedicine, and multifunctional microparticles and nanoparticles in the solid-state as dry powder inhalation aerosols in the targeted treatment and prevention of several pulmonary diseases. These microparticulate/nanoparticulate dry powders, which are targeted directly to the lung as dry powder inhalers, are biocompatible, biodegradable, mucopenetrating, and provide sustained drug release.
We utilize various types of inhaler devices for both in vitro and in vivo rodent animal models. A systematic Quality-by-Design (QbD) approach in the solid-state is used and includes comprehensive physicochemical characterization, design of experiments (DOEs), performance modeling, and prediction. Pulmonary diseases with unmet medical needs that we investigate in vitro and in vivo include lung transplantation, lung cancer, infectious diseases, lung inflammatory fibrotic diseases, and autoimmune diseases. Our research program includes translational medicine, as exemplified by several successful collaborations with physician-scientists.
Postdoctorate, University of North Carolina-Chapel Hill, 2006 - 2008
Postdoctorate, University of Wisconsin-Madison School of Pharmacy, 2004
PhD, Pharmaceutical Sciences (Pharmaceutics & Drug Delivery), University of Wisconsin-Madison, 2003
PhD, University of Wisconsin-Madison Department of Chemistry, 12/1999
BS, Pharmacy, University of Wisconsin-Madison, 1996