Nathan Cherrington, PhD, ATS

Associate Dean, Research
Director, Southwest Environmental Health Sciences Center
Director, Center for Toxicology
Professor, Pharmacology and Toxicology
1885 Society Distinguished Scholar

Nathan Cherrington, PhD, ATS, associate dean for research and professor, Pharmacology and Toxicology—directs the NIEHS P30 Southwest Environmental Health Sciences Center and the NIEHS T32 Training in Environmental Toxicology of Human Disease. He also serves as interim director for the College's Center for Toxicology, and holds joint appointments as professor, Clinical Translation Services and in the Mel & Enid Zuckerman College of Public Health, University of Arizona.

Author of more than 200 journal articles and abstracts about drug metabolism and disposition, especially related to liver damage, Cherrington sits on several editorial boards. The 1885 Society Distinguished Scholar and Fellow, Academy of Toxicological Sciences received 19 grants and holds two patents.

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Education & Post Graduate Training: 

Postdoctoral Training, Toxicology, University of Kansas Medical Center, 2002
PhD, Toxicology, North Carolina State University, 1997
BS, Zoology, Brigham Young University (Provo, Utah), 1993

Areas of Research: 

Adverse drug reaction
Drug metabolism and distribution
Gene expression/polymorphisms
Phenoconversion
Hepatic and renal ontogeny
Non-alcoholic steatohepatitis
Blood-testis barrier
 

Professional Organizations: 

Society of Toxicology
American Society for Pharmacology and Experimental Therapeutics

Select Publications

2018

Li H, Toth E, Cherrington NJ. "Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis." Toxicol. Sci.. 2018;164(2):428-438. PMID: 29718361
Li H, Toth E, Cherrington NJ. "Asking the Right Questions With Animal Models: Methionine- and Choline-Deficient Model in Predicting Adverse Drug Reactions in Human NASH." Toxicol. Sci.. 2018;161(1):23-33. PMID: 29145614
Dzierlenga AL, Cherrington NJ. "Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis." J. Biochem. Mol. Toxicol.. 2018;32(3):e22035. PMCID: PMC5854531  PMID: 29341352

2017

Lee S, Kim S, Hwang S, Cherrington NJ, Ryu D-Y. "Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease." Oncotarget. 2017;8(38):63370-63381. PMCID: PMC5609929  PMID: 28968997
Li H, Canet MJ, Clarke JD, et al. "Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis." Drug Metab. Dispos.. 2017;45(12):1317-1325. PMCID: PMC5697442  PMID: 28986475