Pharmacology and Toxicology Department Highlights: January 2023

Publications

ABHIJIT DATE
Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation
Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques

XINXIN DING
Machine learning-assisted identification and quantification of hydroxylated metabolites of polychlorinated biphenyls in animal samples
In vitro airway models from mice, rhesus macaques, and humans maintain species differences in xenobiotic metabolism and cellular responses to naphthalene

XINXIN DING & QING-YU ZHANG
Detection of transgene location in the CYP2A13/2B6/2F1-transgenic mouse model using optical genome mapping technology
Probing the role of CYP2 enzymes in the atropselective metabolism of polychlorinated biphenyls using liver microsomes from transgenic mouse models

AUSTIN THOMPSON, JAROSLAV JANDA, & RICK SCHNELLMANN
A Refined Protocol for the Isolation and Monoculture of Primary Mouse Renal Peritubular Endothelial Cells

DONNA ZHANG, ELI CHAPMAN & AIKSENG OOI
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP