Pharmacy Practice and Science Department Highlights: February 2022

(February 1, 2022)

Publications

Shared Gene Expression and Immune Pathway Changes Associated with Progression from Nevi to Melanoma. Cancers 2022, 14, 3.

  • Borden, E.
  • Adams, A.
  • Buetow, K.
  • Wilson, M.
  • Bauman, J.
  • Curiel-Lewandrowski, C.
  • Chow, H.
  • Bonnie LaFleur, PhD
  • Hastings, K.

Early oral switch to combined cefixime therapy for management of osteoarticular infections in pediatric sickle cell disease patients: a descriptive analysis. Journal of Infection and Public Health 2022;15:1-6.

  • Mohzari, Y.
  • Alshuraim, R.
  • Asdaq, S.
  • Aljobair, F.
  • Alrashed, A.
  • Alsowaida, Y.
  • Alamer, A.
  • Al Munjem, M.
  • Al Musawa, M.
  • Hatata, M.
  • Alzaaqi, M.
  • Binrokan, A.
  • Alajlan, S.
  • Ivo Abraham, PhD, RN
  • Alamer, A.

Expanded access to anticancer treatments from conversion to biosimilar pegfilgrastim-cbqv in US breast cancer patients. Future Oncology 2022;18:363-373

Trilaciclib and the economic value of multilineage myeloprotection from chemotherapy-induced myelosuppression among patients with extensive-stage small cell lung cancer treated with first-line chemotherapy. Journal of Medical Economics 2021;24(Suppl 1):71-83.

Economic evaluation using dynamic transition modeling of ebola virus vaccination in lower-and-middle-income countries. Journal of Medical Economics 2021;24(Suppl 1):1-13.

Economic evaluation of polatuzumab-bendamustine-rituximab vs tafasitamab-lenalidomide in transplant-ineligible relapsed or refractory diffuse large B-cell lymphoma using classical and novel metrics. Journal of Medical Economics 2021;24(Suppl 1):14-24.

Comparing jurisdiction-specific pharmaco-economic evaluations using medical purchasing power parities. Journal of Medical Economics 2021;24(Suppl 1):34-41.

  • Choi, B.
  • Abraham, R.
  • Halawah, H.
  • Calamia, M.
  • Obeng-Kusi, M.
  • Alrawashdh, N.
  • Arku, D.
  • Ivo Abraham, PhD, RN

Is there still a role for talimogene laherparepvec (T-VEC)? An indirect efficacy comparison of T-VEC plus ipilimumab combination therapy versus T-VEC alone as salvage therapy in unresectable metastatic melanoma. Expert Opinion on Biological Therapy 2021;21:1647-1653

Conversion to biosimilar pegfilgrastim-cbqv enables budget-neutral expanded access to FOLFIRINOX treatment for metastatic pancreatic cancer. Future Oncology 2021;17:4561-4570

Far Upstream Binding Protein 1 Participates in Translational Control of Nrf2 Protein Under Oxidative Stress Redox Biology 2021 May; 41:101906.

Nrf2 for Cardiac Protection: Pharmacological Options Against Oxidative Stress Trends Pharmcol Sci. 2021 Sept 42(9): 729-744

N-Acetylcysteine for Cardiac Protection during Coronary Artery Reperfusion: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front. Cardiovasc. Med. Nov 19, 2021.

Randomized Pilot Trial on Optimal Treatment Strategy, Myocardial Change, and Prognosis of Patients with Myocardial Infarction with Nonobstructive Coronary Artery (MINOCA) Am J Med 135 (1): 103-109. Jan 1, 2022

  • Serpytis, R.
  • Majauskiene, E.
  • Navickas, P.
  • Lizaitis, M.
  • Glaveckaite, S.
  • Rucinskas, K.
  • Petrulioniene, Z.
  • Valeviciene, N.
  • Samalavicius, R.
  • Berukstis, A.
  • Baranauskas, A.
  • Gargalskaite, U.
  • Laucevicius, A.
  • Qin Chen, PhD
  • Alpert, J.
  • Serpytis, P.

Nrf2 for Protection Against Oxidant Generation and Mitochondrial Damage in Cardiac Injury Free Radical Biol. Med. 179, Feb 2022, 133-143

Nrf2 Signaling in Heart Failure: Expression of Nrf2, Keap1, Antioxidant and Detoxification Genes in Dilated or Ischemic Cardiomyopathy Physiol. Genomics, (In press)

The Essential Research Curriculum for Doctor of Pharmacy Degree Programs: 2021 Update. J Am Coll Clin Pharm. 2022 [In Press]

Elucidation of Cellular Contributions to Heparin-Induced Thrombocytopenia Using Omic Approaches. Front Pharmacol. 2022 [In Press]

PharmGKB Summary: Heparin Induced Thrombocytopenia (HIT) Pathway. Pharmacogenet Genomics. 2022 [In Press]


Presentations

Qin Chen, PhD gave the following two invited talks on Precision Medicine of Heart Failure to: 7th Meeting on Acute Cardiology and Emergency Medicine in Vilnius, Lithuania (Sept, 2021) and Moscow Cardiology Congress in Moscow, Russia (Oct, 2021).


Kudos

Nancy Alvarez, PharmD, BCPS was elected to a three-year term on the Board of Directors for the American Institute for the History of Pharmacy.

Bonnie LaFleur, PhD is co-I on a newly funded DoD grant with Kathy Rodgers (Associate Director, Translational Neuroscience, Center for Innovations in Brain Science and Professor, Pharmacology) to study " Biomarker Development for the Evaluation of Mas Agonist, RASRx1902, in Amyotrophic Lateral Sclerosis.”