Pharmacology and Toxicology Department Highlights: May 2019
May 10, 2019
(May 10, 2019)
Publications
Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity. Toxicon. 2019 Apr 15;162:1-8. doi: 10.1016/j.toxicon.2019.03.002. Epub 2019 Mar 5.
- Nathan Cherrington, PhD, ATS
- Anika Dzierlenga
- Tarana Arman
- Erica Toth
- Hui Li
- Katherine D. Lynch
- Dan-Dan Tian
- Michael Goedken
- Mary F. Paine
Discovery of Quinoline Analogues as Potent Antivirals against Enterovirus D68 (EV-D68). J. Med. Chem., 2019 Apr 3. doi: 10.1021/acs.jmedchem.9b00115. [Epub ahead of print]
- Jun Wang, PhD
- Rami Musharrafieh
- Jiantao Zhang
- Peter Tuohy
- Naoya Kitamura
- Shreya Sai Bellampalli
- Yanmei Hu
- Rajesh Khanna
Identification of NMS-873, an allosteric and specific p97 inhibitor, as a broad antiviral against both influenza A and B viruses. Eur. J. Pharm. Sci. 2019 Mar 28;133:86-94. doi: 10.1016/j.ejps.2019.03.020. [Epub ahead of print]
- Jun Wang, PhD
- Jiantao Zhanga
- Yanmei Hu
- Raymond Hua
- Rami Musharrafieh
- Chunlong Ma
- Xu Zhou
- Yin Chen
Presentations
- Gave an invited talk at the Department of Molecular Medicine, University of South Florida. April 5, 2019.
- Gave an invited talk at the Wadsworth Center, New York State Department of Health. It was a great opportunity to not only broadcast Dr. Wang’s antiviral drug discovery program, but also to get in touch with leading virologists and microbiologist at the Wadsworth Center to explore collaboration opportunities. April 18, 2019
- Presented a poster entitled “Molecular Modeling of Drugs for Prediction of Their Physical, Chemical, and Biological Properties “ at the 2019 First Year Project Honor's College Showcase. Created in collaboration with Kayla Bansback, UA Honor’s College undergraduate freshman. April 18, 2019.
- Presented a poster entitled “Particle Engineering of Surfactant Protein A (SPA) Peptide as a Novel Dry Powder Inhaler“ at the Discover BIO5 Research to Innovation Showcase. Created in collaboration with Drs. Priya Muralidharan, Ernest L. Vallorz, Saiful Islam, Monica Kraft, Stephen M. Black, and Julie G. Ledford. This research work is currently funded by NIH NIAID R21 AI135935 grant award with Drs. Julie Ledford and Heidi Mansour and Co-Investigators Drs. Steve Black and Monica Kraft. April 18, 2019.
Kudos
- Received new federal funding from NIH NIDA for a 5-year grant award entitled "MOR/DOR Heterodimer Antagonists: A Novel Treatment for Opioid Dependence." Researched in collaboration with Dr. Michael Morgan at Washington State University and UA faculty colleagues Drs. Streicher, Polt, and Hruby.