Associate Professor, Pharmacology and Toxicology, Drug Discovery & Development

The Chapman lab is a chemical biology lab. They are primarily focused on finding synthetic small molecules or natural probes and leads through targeted approaches, on understanding the mechanisms and modes of action of these molecules, and on improving the molecules through medicinal chemistry. We use contemporary molecular biology and protein biochemistry procedures to produce the desired target proteins and then develop assays amenable to moderate to high throughput screening.

Professor, Pharmacogenomics,
Director, Pharmacogenomics
Holsclaw Endowed Professorship, Pharmacogenomics

Dr.

Professor, Pharmacology and Toxicology
R. Ken and Donna Coit Endowed Chair in Drug Discovery

Hongmin Li, PhD, joined the College of Pharmacy, University of Arizona Tucson in 2020 from the Wadsworth Center, New York State Department of Health. During the last 20 years, my laboratory focuses on both basic and translational sciences. In basic science part, we investigate the structures, functions and mechanisms of essential macromolecules involved in various cellular actions and disease processes.

Dean, R. Ken Coit College of Pharmacy
Howard J. Schaeffer Endowed Chair in Pharmaceutical Sciences
Professor, Pharmacology & Toxicology
National Advisory Board Member

Rick G. Schnellmann, PhD, is dean endowed chair of the University of Arizona R. Ken Coit College of Pharmacy and holds the Howard J Schaeffer in Pharmaceutical Sciences Endowed Chair. A leading pharmacologist, researcher and drug discovery entrepreneur, he joined the UA in August 2016 from the Medical University of South Carolina.

Associate Professor, Pharmacology and Toxicology

Sun's research activities are directed toward discovering new agents that are more selective for cancer cells than normal cells with novel mechanisms of action, elucidating the mechanisms of action of novel natural products with antineoplastic activity, and understanding drug resistance mechanisms in human cancer cells to anticancer drugs.  His laboratory's research projects focus on three specific areas, as described below.

Professor, Pharmacology and Toxicology
Director of Graduate Studies
Member, University of Arizona Cancer Center

Georg T. Wondrak, PhD, is a professor of pharmacology and toxicology within the R. Ken Coit College of Pharmacy. 

Redox Drug Discovery Targeting Skin Cancer and Solar Photodamage

My drug discovery research program examines the pathological role of oxidative and proteotoxic stress in skin carcinogenesis and solar photodamage. The following synergistic research projects are currently pursued in the Wondrak laboratory:

Professor, Pharmacology and Toxicology
R. Ken and Donna Coit Endowed Chair in Drug Discovery

Greg Thatcher, PhD, joined the University of Arizona in 2020 from the University of Illinois College of Pharmacy. In his career, he has graduated over 50 students with PhD’s and a dozen with MSc’s and mentored 40 undergraduate researchers, the majority while on faculty in the Chemistry Department at Queen's University in Canada from 1988 until 2002. These trainees have proceeded to positions in biotech, pharma, business, education, and academia in the USA, Canada, Europe, India, and China.

Co-Director, Arizona Center for Drug Discovery
Professor, Pharmacology and Toxicology

As Co-Director of the Arizona Center for Drug Discovery and professor in the Department of Pharmacology and Toxicology, Dr. Wang is responsible for advancing the mission of drug discovery at the UA Health Sciences, main campus and the Phoenix Biomedical Campus. By uniting the UA’s state-of-the-art facilities, expertise and resources, he will help facilitate drug discovery and development while enhancing translational research collaboration. Dr.

Assistant Professor, Pharmacology & Toxicology

The Xiong lab is focused on the structure-based design of bioactive molecules to modulate disease-causing proteins or genes. We use modern molecular biology tools to develop biochemical, biophysical, and cellular assays to screen and optimize molecules for various therapeutic targets. Our projects also heavily utilize X-ray crystallography and computational modeling to guide molecule design. Two novel molecules developed from this pipeline successfully entered human clinical trials for treating advanced breast cancer (NCT03201913: Xiong R., et al., J Med Chem.

Musil Family Endowed Chair in Drug Discovery
Associate Director of Superfund Research Program
Professor, Pharmacology and Toxicology

The key scientific questions Dr. Zhang's lab is addressing include: