Xinglong Wang

Alzheimer’s disease is the most prevalent form of dementia characterized by neuronal loss in the neocortex and hippocampus. Parkinson's disease is the second most common neurodegenerative disease after Alzheimer's disease due to the progressive loss of dopaminergic neurons in the substantia nigra. Frontotemporal dementia is the second most common form of early-onset dementia caused by neuronal loss in the frontal and temporal cortex. Amyotrophic lateral sclerosis is the most common motor disease characterized by progressive motor neuron degeneration in brain stem and spinal cord. My research interest is to understand the mechanism(s) underlying neuronal death in various major neurodegenerative diseases with a focus on Alzheimer’s disease, Parkinson's disease, Frontotemporal dementia, and Amyotrophic lateral sclerosis.