Current study aimed to develop lipid dispersions of poorly water soluble exemestane by employing lipid carriers such as Gelucire 44/14 and TPGS with porous calcium silicate (PCS) as an adsorbent carrier and formulate into a solid dosage form. The lipid dispersions at 1:5 ratio showed the highest solubility and dissolution compared to pure exemestane. Further, the ex vivo intestinal permeation studies showed improved apparent permeability (P, cm/s) of exemestane from the lipid dispersions (GLD 1.3 × 10cm/s; TLD 1.8 × 10cm/s) compared to pure exemestane (0.7 × 10cm/s). The optimized lipid dispersions (GLD and TLD) were evaluated for scalability to develop into capsules.