Ruiyu Xie, PhD

I am currently doing my post-doctoral training in the laboratory of Dr. Maike Sander at UCSD. My project is to study epigenetic programs underlying pancreas development using human embryonic stem cells (hESCs) Cyt49 as a model system. In recent years, pancreas islet cell transplantation has become a viable option to eliminate the need for frequent insulin injections in type I diabetic patients. However, this approach is hampered by a lack of cadaveric islets. As such, much effort has been expended to generate insulin-producing ?-cells from hESCs to meet this shortfall. Findings from this project will provide molecular cues that regulate the differentiation of pancreatic progenitors into ?-cell.
Pharmacology and Toxicology
Pharmacology and Toxicology
Postdoctoral Fellow, University of California at San Diego
Dissertation Title: 
“Reactive Oxygen Species-induced Necrotic Cell Death”
Career Type: