Kylee Eblin, PhD

I recently completed the PhD program in pharmacology and toxicology and currently work as a research toxicologist at SC Johnson and Son, Inc. My dissertation research focused on low, environmentally relevant levels of arsenicals induce transformation in human bladder cells by the production of ROS and altered MAPK signaling.
I am currently in product safety in the RD & E department working on global fragrancing, home cleaning, and furniture/floor product lines providing regulatory and safety support for consumer products.
Pharmacology and Toxicology
Pharmacology and Toxicology
Director - Registration and Regulatory Compliance, Asia Pacific at SC Johnson Pudongxin District, Shanghai, China
Dissertation Title: 
“The Effects of Arsenical-Induced Reactive Oxygen Species on Human Bladder Cells”
1. Bredfeldt TG, Jagadish B, Eblin KE, Mash EA, Gandolfi AJ. Monomethylarsenous acid induces transformation of human bladder cells. Toxicology and Applied Pharmacology, 216:69-79, 2006.
2. Eblin KE, Bowen ME, Cromey D, Bredfeldt TG, Lau SS, Mash EA, Gandolfi AJ. Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture.  Toxicology and Applied Pharmacology, 217:7-14, 2006.
3. Eblin KE, Bredfeldt TG, Buffington S, Gandolfi AJ. Mitogenic, pro-inflammatory signal transduction caused by monomethylarsonous acid in UROtsa cells. Toxicological Sciences, 95(2): 321-330, 2007.
4. Wang, X.J., Sun, Z., Eblin, K.E., Gandolfi, A.J., and Zhang, D.D., 2007. Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity. Toxic. Appl. Pharm, 225(2), 206-13.
5. Eblin KE, Hau A, Jensen TJ, Buffington SE, Futscher BW, Gandolfi AJ. The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: Acute studies. Toxicology, accepted June 2008. 
6. Eblin KE, Bredfeldt TG, Gandolfi AJ. Possible Mechanisms of Arsenic-Induced Bladder Cancer: A review of UROtsa cells as a model. Toxicology, 27 (248), 67-76, 2008.
7. Jensen TJ, Novak P, Eblin KE, Gandolfi AJ, Futscher BW. Epigenetic Remodeling During Arsenical-Induced Malignant Transformation, Carcingenesis, 2008 Apr 30.
8. Eblin, KE, Jensen TJ, Buffington SE, Hau A, Futscher BW, Gandolfi AJ. The role of reactive oxygen species in the transformation of UROtsa cells: Chronic studies. Accepted with revisions, June 2008.
Career Type: