Joseph Tillotson, PhD

Research and career development.
Pharmacology and Toxicology
Pharmacology and Toxicology
Post Doctoral Fellow, Academic research at John Hopkins Medicine
Dissertation Title: 
Targeting Enzymes Invlovled in Protein Translation and Quality Control as Potential Cancer Therapeutics
Year Enrolled: 

BS Forensic Science (2011), Chaminade University, 

Honors and Achievements: 
1. NIEHS Training Grant-Environmental Toxicology of Human Diseases, 2014, 2015 (34, 35).
1. Tillotson, J., Bashyal, B.P., Kang, M.J., Shi, T., de la Cruz, F., Gunatilaka, A.A.L. and Chapman, E. Selective inhibition of p97 by chlorinated analogues of dehydrocurvularin. Organic and Biomolecular Chemistry. Epub

2. Wijeratne, E.M.K., Gunaherath, G.M., Chapla, V.M., Tillotson, J., de la Cruz, F., Kang, M.J., U Ren, J.M., Araujo, A.R., Arnold, A.E., Chapman, E. and Gunatilaka, A.A.L. (2016). Oxaspirol B with p97 inhibitory activity and other oxaspirols from Lecythophora sp. FL1375 and FL1031, endolichenic fungi inhabiting Parmotrema tinctorum and Cladonia evansii. Journal of Natural Products. 79(2):340-52

3. Tao, S., Tillotson, J., Wijeratne, E.M.K., Xu, Y.M., Kang, M.J., Wu, T., Lau, E.C., Mesa, C., Mason, D.J., Brown, R.V., La Clair, J.J., Gunatilaka, A.A.L., Zhang, D.D. and Chapman, E. (2015). Withaferin A analogs that target the AAA+ chaperone p97. ACS Chemical Biology. 10(8):1916-24

4. Kang, M.J., Wu, T., Wijeratne, E.M.K., Lau, E.C., Mason, D.J., Mesa, C., Tillotson, J., Zhang, D.D., Gunatilaka, A.A.L., La Clair, J.J. and Chapman, E. (2014). Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action. ChemBioChem. 15(14):2125-31


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