Pharmacology and Toxicology Department Highlights: February 2026
March 1, 2026
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Publications
Robin Polt
Biologically Active Truncated Glycopeptides Derived from Pituitary Adenylate Cyclase Activating Polypeptide
Xinxin Ding
Domanico MC, Carratt SA, Collette N, Ubick EA, Edwards PC, Yang W, Buchholz BA, Ding X, Van Winkle LS. Naphthalene-DNA Adduct Formation in a Lung Airway Explant Model: The Role of Bioactivation and Naphthalene Metabolites. Chem Res Toxicol. 2026 Feb 23. doi: 10.1021/acs.chemrestox.5c00428. Epub ahead of print. PMID: 41730518.
Domanico MC, Carratt SA, Collette N, Ubick EA, Edwards PC, Yang W, Buchholz BA, Ding X, Van Winkle LS. Naphthalene-DNA Adduct Formation in a Lung Airway Explant Model: The Role of Bioactivation and Naphthalene Metabolites. Chem Res Toxicol. 2026 Feb 23. doi: 10.1021/acs.chemrestox.5c00428. Epub ahead of print. PMID: 41730518.
Li Z, Li M, Lu J. Biomimetic liposomes in drug delivery: from design mechanisms to applications. Chem Soc Rev. 2026 Jan 26;55(2):1008-1038. doi: 10.1039/d5cs00440c. PMID: 41364452; PMCID: PMC12688027.
Singh V, Jaganathan D, Corro J, Chen K, Kumar Samrat S, Zhang R, Ma M, Battaile KP, Li Z, Zhang QY, Xiong R, Ojha AK, Li H. Structure, Function, and Inhibition of Adenylosuccinate Lyase (ADSL) from Mycobacterium tuberculosis. ACS Infect Dis. 2026 Jan 9;12(1):74-90. doi: 10.1021/acsinfecdis.5c00442. Epub 2025 Dec 8. PMID: 41358587; PMCID: PMC12812255.
Thieulent CJ, Sarkar S, Carossino M, Bhowmik M, Zhu H, Balasuriya UBR. Cell Surface Vimentin Is an Attachment Factor That Facilitates Equine Arteritis Virus Infection In Vitro. Viruses. 2026 Jan 15;18(1):113. doi: 10.3390/v18010113. PMID: 41600875; PMCID: PMC12846471.
Becktel DA, Le EH, Frye JB, Whitman SA, Schnellmann RG, Doyle KP. 2-Hydroxypropyl-β-cyclodextrin accesses acute and subacute infarcts in a mouse model of ischemic stroke. Fluids Barriers CNS. 2026 Jan 28;23(1):32. doi: 10.1186/s12987-026-00767-9. PMID: 41606744; PMCID: PMC12924335.
Inkster AM, Bozack AK, Lemos B, Lumour-Mensah T, Mukherjee SK, Ekramullah SM, Arman DM, Islam J, Wang X, Liang L, Finnell RH, Mazumdar M, Cardenas A. Associations of arsenic exposure and folate in maternal leukocyte DNA methylation: a case-control study of mothers with spina-bifida affected children. Environ Health. 2026 Jan 16;25(1):13. doi: 10.1186/s12940-025-01254-8. PMID: 41546076; PMCID: PMC12896015.
Grants
Picchioni Endowment Fund, $10,000
Picchioni Endowment Fund, $5,000
Patents
Christopher Hulme
Christopher Foley, Christopher Hulme: Patent #12,528,810, Small Molecule Inhibitors of DYRK/CLK and Uses Thereof