Pharmacology and Toxicology Department Highlights: June 2022

(June 1, 2022)


PF-07321332 (Nirmatrelvir) Does Not Interact with Human ENT1 or ENT2: Implications for COVID-19 Patients Clinical and Translational Science (2022) May 3. doi: 10.1111/cts.13292. Online ahead of print. PMID: 35505633

Hypochlorous Acid: From Innate Immune Factor and Environmental Toxicant to Chemopreventive Agent Targeting Solar UV-Induced Skin Cancer Frontiers in Oncology (2022) Apr 29;12:887220. doi: 10.3389/fonc.2022.887220. eCollection 2022. PMID: 35574306 

Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAFV600E /NRASQ61K malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model Molecular Carcinogenesis (2022) Apr 13. doi: 10.1002/mc.23407. Online ahead of print. PMID: 35417045


Hongmin Li, PhD was invited to give a talk entitled ““Inhibitors targeting flavivirus protease and methyltransferase”, at the Baruch S. Blumberg Institute, Doylestown PA, Apr 4, 2022