Pharmacology and Toxicology Department Highlights: October 2019

(October 1, 2019)


A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68. ACS Infect. Dis.


Heidi Mansour, PhD, RPh

 "Synthesis and Physicochemical Analysis of PLGA-based Nanoparticles for Drug Delivery." NIH BUILDing Scholars Fall Symposium, El Paso, TX. 9/28/19. Authors: Cynthia Bautista, David Encinas, PhD, Brenda Cota, Ernest L. Vallorz, Karen Blohm-Mangone, Rick G. Schnellmann, PhD, and Heidi M. Mansour, PhD. Funded by NIH NIGMS Grant Awards RL5GM118969, TL4GM118971, and UL1GM118970.

Jun Wang, PhD

Invited seminar: “Medicinal chemistry and pharmacology of antivirals." Presented at Stony Brook University and Rutgers University.


Heidi Mansour, PhD, RPh

  • Provisional Patent application for UA invention:
    No. 62/888,826 for UA18-190 Invention: Novel Formulations for Neurosteroids
    Inventors: Roberta Brinton, PhD, Kathleen Rodgers, PhD, Yu Jin Kim, PhD, and Heidi Mansour, PhD
  • New Federal Funding Award:
    New NIH NCI PPG (Program Project Grant) for 5 years 9/10/19-8/31/24. Award 1P01CA229112-01A1
    PD: Clara Curiel-Lewandroski, MD. PIs for Projects and Cores: Clara Curiel-Lewandroski, MD,  Sherry Chow, PhD, Sally Dickinson, PhD, Chengcheng Hu, PhD,  Heidi Mansour, PhD, and Georg Wondrak, PhD

Jun Wang, PhD

Dr. Wang’s group was awarded an STTR grant with Regulonix, a startup company funded by Dr. Rajesh Khanna. This grant will help develop novel potent and selective T-type calcium channel antagonists as potential candidates for the management of chemotherapy-induced peripheral neuropathy. The Wang lab will be responsible for the design, synthesis, characterization, and PK profiling of T-type calcium channel blockers, and Regulonix will be in charge of the in vitro biological assays and in vivo mouse model studies. Read more.

Aikseng Ooi, PhD, Donna Zhang, PhD, and Eli Chapman, PhD were invited speakers at the international Environmental Response V conference in Sendai, Japan, September 12-14, 2019.