The Futscher lab’s primary research focus is cancer epigenetics. We use comprehensive genomic approaches to investigate the epigenomic dysfunction that drives human cancer. The use of genome-wide approaches guarantees the capture of all of the information regarding epigenetic change in human cancer.
From this comprehensive data of the normal and diseased human epigenomes, we employ advanced in silico and molecular biological approaches to generate new knowledge and discover the decisive epigenetic events that drive human carcinogenesis. The long-term objective of these studies is the development of epigenetic markers for toxicant exposure, disease detection and prognostication, and the identification of novel targets for molecularly directed cancer therapy.