Pharmacology and Toxicology Alumni

Dissertation: The Effects of Gene-By-Environment Interactions of Nonalcoholic Steatohepatitis and Polymorphisms of Hepatic Xenobiotic Transporters on Drug Disposition and Toxicity

Dissertation: Chronic Exposure to Arsenite Enhances Influenza Virus Infection in Cultured Cells

Dissertation: "Regulation of Mucin Gene Expression by Aspergillus Fumigatus Infection"

Dissertation: Function and Regulation of Intestinal P450s

Dissertation: The Role of MTK1 in Cell Migration and Extracellular Acidification

Dissertation: The Potential Role of a Novel Metformin-methylglyoxal Imidazolinone Metabolite (IMZ) in Alleviating Complications from T2DM

Dissertation: Identification of Poly(ADP-ribose)-Associated Proteins and their Potential Role in ROS-Mediated Cell Death

Academia

Employer: Postdoctoral Fellow, Vanderbilt University Medical Center, School of Medicine - Dept. of Pharmacology, Nashville, TN
Dissertation: "Characterization of the Stress-Activated Protein Kinase, MEKK3"

Employer: PharmD Candidate, University of Arizona
Dissertation: “Genomic Response of Human Urothelial Cells Exposed Chronically To Monomethylarsonous Acid"

Employer: Postdoctoral Fellow Early Discovery- Lead Discovery Technologies Chicago, IL
Dissertation: “Mechanistic Study of USP15-Dependent Deubiquitination and Characterization of Natural Compounds that Modilate the Nrf2-Keapl Antioxidant Response”

Employer: Scientist 1, Translational Pharmacology, Plexxikon
Dissertation: “The Role of N-Acetyl Transferase in the Mutagenicity of 4-Aminobiphenyl”

Employer: Assistant Professor, Biochemistry Comprehensive Cancer Center, Los Angeles, CA
Dissertation: “Epigenetic Silencing of BRCA1 and Maspin in Sporadic Breast Cancer”

Dissertation: “Determinants of Interindividual Variability in Arsenic Secondary Methylation Efficiency in a Population from Northwest Mexico”

Employer: NIEHS Postdoctoral Trainee, Curriculum in Toxicology at The University of North Carolina at Chapel Hill
Dissertation: “NASH Alters Drug Metabolizing Enzyme and Transporter Expression Resulting in Significant Consequences for Pharmaceutical Disposition and Toxicity"

Employer: Post-Doctoral Fellow at US Environmental Protection Agency (EPA) Cincinnati, OH
Dissertation: “The Role of Serotonin and Vesicular Monoamine Transporters in the Adverse Responses to Methylenedioxymethamphetamine”

Employer: Assistant Professor, Kansas University Cancer Center, Kansas City
Dissertation: “Cloning and characterization of novel isoforms of the human receptor for Prostaglandin F2 Alpha”

Employer: Postdoctoral Fellow, University of California at San Diego
Dissertation: “Reactive Oxygen Species-induced Necrotic Cell Death”

Employer: Research Associate, School of Pharmacy, University of Wisconsin, Madison
Dissertation: “N-Acetylation as Protactive against Hydrazine Hepatoxicity”

Employer: Postdoctoral Fellow, University of California in San Diego
Dissertation: “Activation of Novel Signal Transduction Pathways by Human EP1 Prostanoid Receptor”

Employer: Postdoctoral Research Associate, Department of Pharmacology & Toxicology, University of Utah
Dissertation: “Analysis of Protein Adduction Kinetics and the Effects of Protein Adduction on C-Jun N-Terminal Kinase Signaling”

Employer: Senior Scientist, AstraZeneca Boston, MA
Dissertation: “Identification of Cathepsin B and L as Novel UVA Targets Upstream of Cutaneous Lysosomal-Autophagic Dysregulation”

Employer: Postdoctoral Research Fellow, Massachusetts General Hospital, Harvard Medical
Dissertation: “Pharmacological Modulation of Oxidative and Protestoxic Stress for Antimelanoma Intervention”

Employer: Postdoctoral Fellow at University of North Carolina at Chapel Hill
Dissertation: “Post Transitional Regulation of Nrf2: Novel Mechanisms beyond Keap 1”

Employer: Postdoctoral Fellow, Emory University, School of Medicine Atlanta, GA
Dissertation: “Xenosensor Regulation of Enzymes and Transporters in Drug Exposure and Disease”

Employer: Postdoctoral Research Associate, Michigan State University Lansing, MI
Dissertation: Src is Required for TGFB and Hyaluronan Induced Epicardial Cell Invasion, Differentiation, and Migration

Employer: Postdoctoral Fellow, Yale University
Dissertation: “Protein Interactions Mediated by C2H2 Zinc Finger Proteins”

Employer: Postdoctoral Researcher, University of Pennsylvania, Philadelphia, PA
Dissertation: “Mechanistic Study of Nucleocytoplasmic Trafficking and Reversible Acetylation in Modulating the NRF2-Dependent Antioxidant Response”

Employer: Post-doctoral fellow at Tufts University/Medical Center, Molecular Oncology Research Institute
Dissertation: "Mechanism of Arsenical Toxicity on TGFB Signaling and Genetic Regulation During Embryonic Heart Development"

Employer: Post Doctoral Fellow, UC Berkeley, Berkeley, CA
Dissertation: “Defining the Role of Nucleolin on the Transcriptional Regulation of c-MYC through Modulation of the c-MYC NHE III1 Element”

Employer: Postdoctoral Fellow at Lady Davis Institute, McGill University Montreal, Quebec, Canada
Dissertation: “Arsenite Alters Lysosome-Mediated Degradation and the Autophagy Process Leading to Immunosuppression in Human B-Lymphoblastoid Cell Lines”

Employer: Postdoctoral Fellow, Dept. of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI
Dissertation: "Coordinated Regulation of Hepatic and Renal Membrane Transporters in Experimental Nonalcoholic Steatohepatitis"

Employer: MD Candidate, University of Arizona
Dissertation: “Arsenite and Olfactomedin-1 Regulate Epithelial to Mesenchymal Cell Transition (EMT) in Heart Valve Development”

Employer: Postdoctoral Research Associate I, University of Arizona
Dissertation: “Deciphering the Mechanisms of Resistance and Sensitivity to Histone Deacetylase Inhibitors in Diffuse Large B-cell Lymphoma"

Employer: Postdoctoral fellow for Dr. Kim Boekelheide at Brown University
Dissertation: "Nucleoside Transport at the Blood-Testis Barrier"

Employer: Postdoctoral Researcher, Drexel University College of Medicine
Dissertation: "Calcium Modulation of PARP-mediated DNA Repair"

Employer: Postdoctoral Fellow, University of Wisconsin
Dissertation: "Mechanisms of Has2 Regulation and Hyaluronan Signaling During Embryonic Development"

Employer: Posdoctral Associate at Duke University Durham, North Carolina
Dissertation: “Arsenic Induced Pseudhpoxia In Malignant Transformation:The Role of HIF-1A Mediated Metabolism Distubance”

Employer: ORISE Postdoctoral Fellow at US EPA National Center for Environmental Assessment, University of North Carolina at Chapel Hill
Dissertation: “Mechanisms of Arsenic Enhanced Metabolic Syndrome"

Employer: Postdoctoral Fellow, University of North Carolina at Chapel Hill
Dissertation: “MTK1 Regulates Extracellular Acidification and Cell Migration through the HER2 Breast Cancer Receptor"

Employer: Post Doctoral Fellow, Academic research at John Hopkins Medicine
Dissertation: Targeting Enzymes Invlovled in Protein Translation and Quality Control as Potential Cancer Therapeutics

Employer: : King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), College of Pharmacy
Title:Assistant Professor
Dissertation: DRUG REPURPOSING AS A NOVEL TREATMENT APPROACH FOR MEDULLARY THYROID CARCINOMA

Employer: The University of Arizona
Title:Research Associate

Employer: Research Fellow at Boston Children's Hospital, Hardvard Medical School
Dissertation: Dopamine Induced Post-Translational Modifications of a-Synuclein and the Role of Arsenic in the Development of Parkinson's Disese and other Synucleinopathies

Employer: University of Washington
Title:Postdoctoral Fellow

Government

Employer: Toxicologist, Wisconsin Department of Health Services
Dissertation: “Mechanisms Underlying the Pharmacologic Reversal of Genetic and Epigenetic Components of Tumor Suppressor Gene Silencing in Human Breast Cancer”

Employer: Post Doctoral Fellow, National Institutes of Health NHLBI/TMB
Dissertation: “Distinct Functions of MEKK3 and MEKK4 during Heart Valve Morphogenesis”

Employer: Post-doctoral IRTA Fellow in the Division of the National Toxicology Program, National Institute of Environmental Health Sciences
Dissertation: Mechanism and Functional Consequence of Mrp2 Mislocalization in Nonalcoholic Steatohepatitis

Employer: Post-doctoral Research Fellow at the Oak Ridge Institute for Science and Education (ORISE)
Dissertation: From Molecular Mechanisms of UVA-Induced Skin Photooxidative Stress to Experimental Interventions Targeting Skin Cancer

Health Care

Employer: Post-doctoral Research Fellow at the Mayo Clinic in Arizona
Dissertation: Molecular and chemical modulation of NRF2 for disease intervention

Industry

Employer: Postdoctoral Research Associate, The University of Arizona
Dissertation: “Methylenedioxymethamphetamine-Induced Neurotoxicity: The Role of Hepatic Enzymes Cytochrome P450 2D6 and Catechol-O-Methyltransferase and Contribution of Microglia”

Employer: Senior Scientist, Oridigm Corporation, Seattle, WA
Dissertation: “Photoprotective Actions of Vitamin E in Mouse Skin: Prevention of UVB Induced DNA Photodamage”

Employer: Scientist, Genentech Department of Protein Chemistry, South San Francisco, CA
Dissertation: “The Effects of Arsenic on the Ubiquitin Dependent Proteolytic Pathway”

Employer: Senior Scientist, Pfizer Global Drug Metabolism Pharmacia Corporation
Dissertation: “Steroid Derivatives as Probes of Adrenal Cytochrome P450 Structure and Function”

Employer: Research in Regenerative Stem Cell Biology and/or How Environmental and Lifestyle Factors Predispose the Onset of Chronic Diseases
Dissertation: “Role of In-Utero and Chronic Arsenite Exposure in the Development of Adult Cardiovascular Pathogenesis"

Employer: Senior Research Scientist, Bristol-Myers Squibb, Wilmington, DE
Dissertation: "Fate of Vitamin E in UVB Irradiated Mouse Skin and In Vitro Systems: Antioxidant and Photochemistry"

Employer: Senior Toxicologist, Monsanto Company
Dissertation: "Arsenic: Metabolism, Cytotoxicity and Toxicogenetic Alterations in the Developing Lung"

Employer: Postdoctoral Research Fellow, Texas A&M University
Dissertation: “Derivations of Tissue Slice Technology as Toxicological Screening Systems”

Employer: Toxicologist Additives Team, Toxicology and Health Risk Assessments, Chevron Energy Technology Company, Richmond, CA
Dissertation: “Contribution of Heat Shock Protein 27 and Retinol Binding Protein to 11-deoxy-16, 16-dimethyl Prostaglandin E2 Mediated Cytoprotection”

Employer: Director - Registration and Regulatory Compliance, Asia Pacific at SC Johnson Pudongxin District, Shanghai, China
Dissertation: “The Effects of Arsenical-Induced Reactive Oxygen Species on Human Bladder Cells”

Employer: Toxicologist, Center for Toxicology and Environmental Health, LLC Little Rock, AK
Dissertation: “Mechanisms of Malignant Transofrmation of Human Urothelial Cells by Monomethylarsonous Acid”

Employer: Research Scientist II, Gilead Sciences
Dissertation: “Mechanisms of Hepatoprotection during Intrahepatic Cholestasis”

Employer: Medical Research Manager at NAMSA
Dissertation: Combination Therapeutic Strategies Modulating Growth and Metablic Pathways in Prostate Cancer

Employer: Research Scientist, Avila Therapeutics
Dissertation: “Identification and Characterization of Quinone-Thioether Protein Adducts in Vivo”

Employer: Scientist II, Investigational Toxicology Millennium: The Tekeda Oncology Co.
Dissertation: “Non-Alcoholic Fatty Liver Disease Alters the Three Stages of Hepatic Drug Management”

Employer: Senior Scientist, Drug Safety Evaluation Millennium: The Takeda Oncology Company
Dissertation: “Modulation of MAP Kinase signaling by the Tsc-2 Tumore Suppressor and cAMP in Quinol-Thioether-Induced Renal Cell Carcinoma”

Employer: Research Toxicologist S.C. Johnson & Son, Inc. Racine, WI
Dissertation: “The role of the Nrf2-Keapl Pathway in Autophagy and how it Contributes to Arsenic Carcinogenicity"

Employer: Regulatory Specialist, Ecolab, Eagan, MN
Dissertation: "Dicarbonyl protein adduction: plasminogen as a target and metformin as a scavenging therapeutic in type 2 diabetes"

Employer: Staff Scientist, Gilead, San Francisco, CA
Dissertation: “Hepatic Stress Response Mechanisms in Progressive Human Nonalcoholic Fatty Liver Disease"

Employer: Research Associate at Wayne State University
Dissertation: Pentoxifylline as an Adjuvant Thereapy in Renal Cancer

Employer: Toxicologist, Center for Toxicology and Environmental Health (CTEH) Little Rock, AR
Dissertation: “Protein Adduct Formation by Reactive Electrophiles: Identifying Mechanistic Links with Benzene-Induced Hematotoxicity”

Employer: Research Scientist, Ventana Medical
Dissertation: Postpartum Breast Cancer in Hispanic Women: Epigenetics and microRNAs

Employer: Human Safety Toxicologist, Procter and Gamble
Dissertation: Ironing out roles and regulation og NRF2 in a Hereditary cancer syndrome.

Employer: Regulatory Specialist-Innovation Toxicologist at Ecolab, Eagan MN
Dissertation: "Exposure to Arsenite During Fetal Development Increases Susceptibility to Fatty Liver Disease and Alters Hepatic Transport"

Dissertation: Equilibrative Nucleoside Transporter Mediated Drug Disposition Across the Blood-Testis Barrier

Employer: Lovelace Biomedical Research Institute
Title:Research Associate

Employer: BioMarin Pharmaceutical Inc.
Title:Nonclinical Study Manager 2

Employer: Project Toxicologist, Center for Toxicology and Enviromental Health
Dissertation: Epithelial-Mesenchymal transition opens a window of toxicant sensitivity

Other

Employer: Graduate Research Associate at the University of Arizona