MS & PHD STUDENTS

Ritesh Sanghvi, PhD

Degree: 
PhD
Program: 
Pharmaceutical Sciences
Track: 
Pharmaceutics and Pharmacokinetics
Dissertation Title: 
“Drug Solubilization using N-Methyl Pyrrolidone: Efficiency and Mechanism”

Alumnus
Year Graduated: 2006
Associate Research Scientist, Forest Laboratories, Commack, NY

Academic & Professional Updates
I am currently working as a Research Scientist in the preformulation department of Forest Research Institute. My work involves a wide variety of responsibilities including physicochemical profiling and characterization of pharmaceutically active leads; final form selection including screening for salts, polymorphs and co-crystals; develop formulations for early and late phase product development; support formulation and process scale-up activities. Forest Research Institute provides a good opportunity for pursuing independent research in-parallel to the company projects through their new technology platform program. I am utilizing this opportunity to study the factors that influence the solubility of drugs in lipid solvents.

Publications
1. Sanghvi R., Yalkowsky S. H., Estimation of Heat Capacity of Boiling of Organic Compounds, Industrial and Engineering Chemical Research, 2006, 45(1), 451-453.
2. Sanghvi R., Yalkowsky S. H., Estimation of the Normal Boiling Point of Organic Compounds, Industrial and Engineering Chemical Research, 2006, 45(8), 2856-2861.
3. Sanghvi R., Evans D., Yalkowsky S.H., Stacking Complexation by Nicotinamide: A useful way of enhancing drug solubility (In press, International Journal of Pharmaceutics).
4. Sanghvi R., Machatha S. G., Narazaki R., Yalkowsky S. H., Drug Solubilization using N-Methyl Pyrrolidone: Efficiency and Mechanism (submitted to Journal of Pharmaceutical Sciences).  5. Narazaki R., Sanghvi R., Yalkowsky S. H., Estimation of drug precipitation upon dilution of pH-controlled formulations (submitted to Journal of Molecular Pharmaceutics).
6. Narazaki R., Sanghvi R., Yalkowsky S. H., Estimation of drug precipitation upon dilution of pH-cosolvent solubilized formulations (submitted to Journal of Pharmaceutical Sciences).
7. Sanghvi R., Machatha S. G., Narazaki R., Tabibi E., Yalkowsky S. H., Solubilization and Preformulation of Antalarmin: A Novel Stress Inhibitor (Submitted to National Cancer Institute for approval).
8. Narazaki R., Wu M., Guo D., Sanghvi R., Yalkowsky S.H., Solubility of Naphthalene derivatives in organic solvents: Role of solute and solvent functional groups (In preparation).
Originally posted: August 21, 2014
Last updated: October 8, 2015
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