Parijat Jain, PhD

Pharmaceutical Sciences
Pharmaceutics and Pharmacokinetics
Dissertation Title: 
“Prediction of Aqueous Solubility from SCRATCH”

Year Graduated: 2008
Senior Scientist, Novartis Pharmaceuticals Corporation, East Hanover, NJ

Academic & Professional Updates
As a Ph.D. student in Pharmaceutics, I was involved in preformulation, formulation, solubilization and stability studies for various drugs and their analogues. I was also involved in studying the solubilization efficiency and mechanism of 2-Pyrrolidone and conducted several oral bioavailability studies on various anticancer drugs for the NCI. My dissertation, 'Prediction of Aqueous Solubility from SCRATCH', primarily focussed on proposing a model to predict aqueous solubility of an organic compound directly from its structure without using any experimental data. The algorithm utilizes predicted melting points and predicted aqueous activity coefficients for the solubility estimation, reflecting the truly predictive nature of the model. Currently, I am employed at Novartis Pharmaceuticals, at East Hanover, NJ, as a Senior Scientist in the Pharmaceutical and Analytical Development group as a formulator. We are responsible for the late phase confirmatory development process which involves clinical supply formulation development, market formulation development, final market image development and eventually the process scale-up activities.
Originally posted: August 21, 2014
Last updated: October 8, 2015
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