April Lake, PhD

Status: 
Alumni
Degree: 
PhD
Program: 
Pharmacology and Toxicology
Track: 
Pharmacology and Toxicology
Dissertation Title: 
“Hepatic Stress Response Mechanisms in Progressive Human Nonalcoholic Fatty Liver Disease"
Honors and Achievements: 
1. Mountain West Society of Toxicology Student Travel Award, 2011.
2. NIEHS Training Grant - Environmental Toxicology of Human Diseases, 2011 (31).
3. Research mentor for Brieanna Flores-Keown, University of Arizona Minority Health Disparities undergraduate summer student program, 2011-12.
4. Research mentor for Nicole Sayers, undergraduate research technicia., 2011-12.
5. Co-Chairperson for the 51st Society of Toxicology Platform Session MicroRNA as Biomarkers for Organ Damage, 2012.
6. Chairperson for the 51st Society of Toxicology Poster Session Liver Disease Models, 2012.
7. Invention Disclosure for NASH preventative therapeutic study in rodent, 2012.
8. Mountain West Society of Toxicology Platform Award, 2012.
9. Society of Toxicology Graduate Student Travel Award, 2012.
10. NIEHS Training Grant - Environmental Toxicology of Human Diseases, 2012 (32).
11. SOT Award, 2nd Place, Carl C. Smith Mechanisms Specialty Section, 2013.
Publications: 
1. Lake, A.D., Novak, P., Shipkova, P., Aranibar, N., Robertson, D.G., R.R. Vaillancourt, Reily, M.D., Lehman-McKeeman, L.D., Vaillancourt, R.R., and N.J, Cherrington (2013).  Branched Chain Amino Acid Catabolism and Signaling in Progressive Stages of Human Nonalcoholic Fatty Liver Disease. Drug Metabol. Disp. Submitted.
2. Canet MJ, Hardwick RN, Lake AD, Kopplin MJ, Scheffer GL, Klimecki WT, Gandolfi AJ, Cherrington NJ. Altered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver Disease. Drug Metab. Disp 40:1817-1824, 2012.
3. Clarke, J.D., Novak, P., Lake, A.D., Shipkova, P., Aranibar, N., Robertson, D., Severson, P.L., Reily, M.D., Futscher, B.W., Lehman-McKeeman, L.D., Cherrington, N.J.: Characterization of Hepatocellular Carcinoma Related Genes and Metabolites in Human Nonalcoholic Fatty Liver Disease. Digestive Diseases and Sciences, 59(2):365-74, 2014.
Alumna or Alumnus: 
Alumna
Alumni Title/Position/Employer: 
Staff Scientist, Gilead, San Francisco, CA
Career Type: 
Industry