Akash Jain, PhD

My research as a student in pharmaceutics focused on developing an in-silico model for predicting physico-chemical properties relevant to drug discovery and design. My dissertation provides a simple and accurate means of melting point prediction for drug like molecules directly from chemical structure. Such model can be very useful in early drug discovery to predict crystallinity and aqueous solubility of drugs even before they are synthesized. My other research projects involved physico-chemical characterization and preformulation of anti-cancer and anti-viral drugs. I was also involved in formulation and characterization of liposome delivery system for anti-cancer agents. The Department of Pharmaceutical Sciences at the University of Arizona provides an exciting environment for learning and education. It all starts with the renowned faculty and incoming students are bound to succeed under their guidance. And it is only appropriate to mention that our alumni are well-placed and highly recognized in academia, industry and elsewhere. I am currently employed at Novartis Institutes for Biomedical Research, Cambridge MA as Senior Scientist in the Chemical and Pharmaceutical Profiling group. My major job responsibilities include pre-clinical formulation support for pharmacokinetic, efficacy and toxicology studies, and selection of physical form and formulation strategies for first-in-human clinical trials on new molecular entities from Cardiovascular and Metabolism, Infectious Diseases and Oncology research programs. In my previous job, I was employed at Synta Pharmaceuticals, Lexington MA as a Formulation Scientist in the Drug Product Development group. My responsibilities included parenteral formulation development of anti-cancer drugs, development and transfer of formulations for IND-enabling toxicological studies and development and manufacturing of clinical formulations for first in human trials. I was also involved in writing protocols, technical reports, and sections of regulatory documents.
Pharmaceutical Sciences
Pharmaceutics and Pharmacokinetics
Dissertation Title: 
“Estimation of Melting Points of Organic Compound”
Alumna or Alumnus: 
Alumni Title/Position/Employer: 
Senior Scientist, Novartis Institues for Biomedical Research, Inc.