Medicinal and Natural Products Chemistry Courses
Specific Required Courses
Principles of Drug Discovery, Design and Development (PHSC 670)
An introduction into principles of drug discovery, design and development covering the process and tools such as computational chemistry, combinatorial chemistry and subjects such as molecular target identification, drug receptor interactions, DNA and proteins as molecular targets, drug metabolism and drug delivery systems.
Organic Reaction Mechanisms (CHEM 541)
Detailed analysis of the factors which influence the rates and courses of organic processes.
Medicinal and Natural Products Chemistry Seminar (PHSC 596a)
The development and exchange of scholarly information, usually in a small group setting. The scope of work shall consist of research by course registrants, with the exchange of the results of such research through discussion, reports, and/or papers.
At least 2 of the following courses:
Chemistry of Natural Products (PHSC 549)
Chemical, biochemical and genetic survey of secondary metabolic pathways leading to biologically active natural products. Combinatorial biosynthesis of hybrid "unnatural" natural products.
Genomics and Proteomics (PCOL 601)
Lecture and laboratory on the qualitative and quantitative effects of toxic substances on mammalian genes and proteins. Modern instrumental techniques will be employed whenever appropriate. Lecture may be taken separately by non-majors. Toxicology majors take lecture/laboratory.
Proteins and Nucleic Acids as Drug Targets (PHSC 530)
This is a new course that is being developed specifically for Biochemistry, Chemistry and Pharmacy (BCP). The course will be coordinated through the Medicinal Chemistry Division of Pharmacology and Toxicology but will be team-taught by the BCP faculty. Each semester four to five topics will be chosen for which all three BCP core areas (chemistry, biochemistry and medicinal chemistry) have been brought to bear on a specific biological question. Three training faculty, one from each core area, will lecture on each topic and lead discussions. Students will present material and lead discussions.
Drug Metabolism and Disposition (PCOL 550)
Principles of absorption, distribution and excretion of drugs, with emphasis on mechanisms of drug metabolism.
Further information
For general questions regarding the graduate programs in the College of Pharmacy, contact Nancy Colbert, program coordinator, (520) 626-7265 or by fax (520)626-2466