Daniel C Malone, PhD
Professor
Department:
Pharmacy Practice and Science
(520) 626-3532
Secondary Phone:
(520) 626-4351
Fax:
(520) 626-5518
E-mail:
Location:
Drachmall Hall B307F
Bio / Research:
Dr. Malone is currently a professor at The University of Arizona College of Pharmacy and Mel and Enid Zuckerman College of Public Health. He is an investigator with the Center for Health Outcomes and Pharmacoeconomic Research and director of the Division of Pharmaceutical Policy within the center. Dr. Malone's area of expertise is in pharmacoeconomics and health services research. He also has extensive experience in pharmacy demonstration projects and economic issues associated with the pharmaceutical industry.
Dr. Malone is currently the co-principal investigator for The University of Arizona Center for Education and Research on Therapuetics (CERT). The AZCERT is one of seven CERTs nationally, funded by the Agency for Healthcare Research and Quality. The primary focus of the AZCERT is drug interactions. Dr. Malone and his colleagues are currently investigating methods to improve safe medication use by reducing clinically important drug-drug interactions. He has also received funding from the Centers for Disease Control and Prevention in the area of drug-drug interactions.
Education:BS, University of Colorado, 1987
MS, University of Texas, 1990
PhD, University of Texas, 1993
Post-doctoral Fellow, University of Washington, 1993-94
Malone DC, Abarca J, Skrepnek GH, Murphy JE, Grizzle AJ, Rehfeld RA, Woosley RL. Pharmacist workload and pharmacy characteristics associated with dispensing of potentially clinically important drug-drug interactions. Medical Care 2007; 45:456-462.
Hess LM, Benham-Hutchins M, Herzog TJ, Hsu CH, Malone DC, Skrepnek GH, Slack MK, Alberts DS. A meta-analysis of the efficacy of intraperitoneal cisplatin for the front-line treatment of ovarian cancer. International Journal of Gynecological Cancer 2007; 17:561-570.
Daniel GW. Malone DC. Characteristics of older adults who meet the annual prescription drug expenditure threshold for medicare medication therapy management programs. Journal of Managed Care Pharmacy 2007; 13:142-154.
Ko Y, Abarca J, Malone DC, Dare DC, Geraets D, Houranieh A, Jones WN, Nichol WP, Schepers GP, Wilhardt M. Practitioners’ views on computerized drug-drug interaction alerts in the VA system. Journal of the American Medical Informatics Association 2007; 14:56-64.
Ko Y, Malone DC, Armstrong EP. A pharmacoeconomic evaluation of antimuscarinic agents for the treatment of overactive bladder. Pharmacotherapy 2006; 26:1694-1702.
Hess LM, Raebel MR, Conner DA, Malone DC. The measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures. Annals of Pharmacotherapy 2006; 40:1280-1288.
Murphy JE, Malone DC, Skrepnek GH, Armstrong EP, Abarca J, Grizzle AJ, Rehfeld R, Woosley RL. The role of technicians in the management of computerized drug-drug interaction alerts in community pharmacies. Journal of Pharmacy Technology 2006; 22:155-160.
Abarca J, Colon LR, Wang VS, Malone DC, Murphy JE, Armstrong EP. Evaluation of drug-drug interaction screening software in community and hospital pharmacies. Journal of Managed Care Pharmacy 2006; 12:383-389.
Perkins NA, Murphy JE, Armstrong EP, Malone DC. Performance of drug-drug interaction software for personal digital assistants. Pharmacotherapy 2006; 40:850-855.
Johnson L, Strich H, Taylor A, Timmerman B, Malone D, Teufel-Shone N, Drummond R, Woosley R, Pereira E, Martinez A. Use of herbal remedies by diabetic Hispanic women in the Southwestern United States. Phytotherapy Research 2006:20: 250-255.
Skrepnek GH, Armstrong EP, Malone DC, Abarca J, Murphy JE, Grizzle AJ, Rehfeld RA, Woosley RL. Workload and the availability of technology in community pharmacy practice. Journal of the American Pharmacist Association 2006; 46(2):154-160.
Abarca J, Malone DC, Skrepnek GH, Rehfeld RA, Murphy JE, Grizzle AJ, Armstrong EP, Woosley RL. Community pharmacy managers’ perception of computerized drug-drug interaction alerts. Journal of the American Pharmacist Association 2006; 46(2):148-153.
Hess LM, Sadoda K, Malone DC, Salache S, Warneke J, Alberts DS. Adherence assessment using medication weight in a phase IIb clinical trial of difluoromethylornithine for the chemoprevention of skin cancer. Cancer Epidemiology and Biomarkers Prevention 2005; 14:2579-2583.
Malone DC, Tran TT, Poordad FF, Cost-efficacy analysis of peginterferon alfa-2b plus ribavirin compared with peginterferon alfa-2a plus ribavirin for the treatment of chronic hepatitis C. Journal of Managed Care Pharmacy 2005; 11:687-94.
Skrepnek GH, Abarca J, Malone DC, Armstrong EP, Shirazi FM, Woosley RL. Incremental effects of concurrent pharmacotherapeutic regimens for heart failure on hospitalizations and costs. Annals of Pharmacotherapy 2005; 39:1785-91.
Malone DC, Hutchins DS, Haupert H, Hansten P, Duncan B, Van Bergen RC, Solomon SL, Lipton RB. Assessment of potential drug–drug interactions with a prescription claims database. American Journal of Health-Systems Pharmacy 2005 62: 1983-1991.
Olson BM, Malone DC, Zachry WM, Coons SJ. Consumer understanding and satisfaction associated with a 3-tier prescription drug benefit. Journal of Managed Care Pharmacy 2005; 11:480-492.
Malone DC, Raebel MA, Porter JA, Lanty FA, Conner DA, Gay EC, Merenich JA, Vogel EA. Cost-effectiveness of sibutramine in the LOSE weight study: evaluating the role of pharmacological weight-loss therapy within a weight management program. Journal of Managed Care Pharmacy 2005; 11:458-468.
Romero AV, Malone DC. Accuracy of adverse-drug-event reports collected using an automated dispensing system. American Journal of Health-System Pharmacy 2005; 62:1375-1380.
Joish VN, Malone DC, Wendel C, Draugalis JR, Mohler MJ. Development and validation of a diabetes severity index (DSI): a risk adjustment tool for predicting healthcare resource use and costs. Pharmacotherapy 2005; 25:676-684.
Skrepnek GH, Armstrong EP, Malone DC, Ramachandran S. An economic and outcomes assessment of first-line monotherapy in the treatment of community-acquired pneumonia within managed care. Current Medical Research & Opinion 2005; 21(2):261-70.
Abarca J; Malone DC; Armstrong EP; Grizzle AJ; Cohen MD. Longitudinal analysis of the use of etanercept versus infliximab determined from a medical chart audit. Journal of Managed Care Pharmacy 2004; 10:538-542.
Raebel MA, Malone DC, Conner DA, Xu S, Porter JA, Lanty FA. Health services use and health care costs of obese and non-obese health maintenance organization members. Archives of Internal Medicine 2004: 164:2135-2140.
Armstrong EP, Zachry WM III, Malone DC. Cost-effectiveness analysis of simvastatin and lovastatin/extended-release niacin to achieve LDL and HDL goal using NHANES data. Journal of Managed Care Pharmacy 2004; 10:251-258.
Malone DC, Abarca J, Hansten PD, Grizzle AJ, Armstrong EP, Van Bergen R, Duncan-Edgar BS, Solomon SL, Lipton RL. Identification of serious drug-drug interactions: results of the partnership to prevent drug-drug interactions. Journal of the American Pharmacist Association 2004: 44:142-151.
Abarca J, Malone DC, Armstrong EP, Grizzle AJ, Hansten PD, Van Bergen R, Lipton RB. Concordance of major drug interaction classifications among drug interaction compendia. Journal of the American Pharmacist Association 2004; 44:136-141.
Joish V, Malone DC, Wendal C, Mohler MJ. Profiling quality of diabetes care in a Veterans Affairs health care system. American Journal of Medical Quality 2004; 19(3);112-120.
Abarca J, Malone DC, Armstrong EP, Zachry III WM. Use of ace inhibitor therapy among patients with congestive heart failure enrolled in a managed care organization: the effect on hospitalization and costs. Pharmacotherapy 2004; 24: 351-357.
Malone DC, Luskin AT. Hydrofluoroalkane-134a beclomethasone as a dominant economic asthma therapy. Respiratory Medicine 2003; 97:1269-1276.
Lackner TE, Heard T, Glunz S, Gann N, Babington M, Malone DC. Gastrointestinal disease control after histamine2-receptor antagonist dose modification for renal impairment in frail chronically-ill elderly patients. Journal of the American Geriatrics Association 2003; 51:650-656.
Lee EK, Malone DC. Comparison of peptic ulcer drug use and expenditure before and after separation of prescribing and dispensing policy in Korea. Clinical Therapeutics 2003; 25: 578-592.
Armstrong EP, Malone DC. The impact of nonsteroidal anti-inflammatory drugs on blood pressure, with an emphasis on newer agents. Clinical Therapeutics 2003; 25:1-18.
Armstrong EA, Malone DC. Fluticasone propionate is associated with lower asthma-related costs than leukotriene modifiers in a real-world analysis. Pharmacotherapy 2002; 22(9):1117-1123.
Malone DC, Armstrong EP. Economic burden of asthma: implications for outcomes and cost-effectiveness analysis. Expert Review of Pharmacoeconomics & Outcomes Research 2001; 1:177-186.
Malone DC, Mubarak-Shaban H. Adherence to ATS guidelines for hospitalized patients with community-acquired pneumonia. Annals of Pharmacotherapy 2001; 35:1180-1185.
Okano GJ, Malone DC, Billups SJ, Carter BL, Sintek CD, Covey D, Mason B, Jue S, Carmichael J, Guthrie K, Sloboda L, Dombrowski R, Gereats DR, Amato MG. Reduced quality of life in veterans at risk for drug related problems. Pharmacotherapy 2001; 21(9):1123-1129.
Gonzales R, Malone DC, Maselli JH, Sande MA. Excess antibiotic use for acute respiratory infections in the United States. Clinical Infectious Diseases 2001:33(6):757-762.
Carter BL, Malone DC, Billups SJ, Valuck RJ, Barnette, DJ, Sintek CD, Okano GJ, Ellis SL, Covey D, Mason B, Jue S, Carmichael J, Guthrie K, Sloboda L, Dombrowski R, Gereats DR, Amato MG. The IMPROVE study: how should the findings be interpreted? American Journal Health-Systems Pharmacy 2001: 58:1330-1337.
Malone DC, Carter BL, Billups SJ, Valuck RJ, Barnette, DJ, Sintek CD, Okano GJ, Ellis SL, Covey D, Mason B, Jue S, Carmichael J, Guthrie K, Sloboda L, Dombrowski R, Gereats DR, Amato MG. Can Clinical Pharmacists Affect SF-36 Scores in Veterans at High-Risk For Medication-Related Problems? Medical Care 2001:39:109-112.
Carter BC, Billups SJ, Malone DC, Valuck RJ, Barnette, DJ, Sintek CD. Recommended guidelines for pharmacists who provide care for patients in the IMPROVE Study. Federal Practitioner 2001; 18(1):38-46.
Ellis SL, Carter BL, Malone DC, Valuck RJ, Barnette, DJ, Sintek CD, Okano GJ, Ellis SL, Covey D, Mason B, Jue S, Carmichael J, Guthrie K, Sloboda L, Dombrowski R, Gereats DR, Amato MG. Clinical and economic impact of ambulatory care clinical pharmacists in management of dyslipidemia in older adults: The IMPROVE Study. Pharmacotherapy 2000; 20(12):1508-1516.
Malone DC, Carter BL, Billups SJ, Valuck RJ, Barnette, DJ, Sintek CD, Okano GJ, Ellis SL, Covey D, Mason B, Jue S, Carmichael J, Guthrie K, Sloboda L, Dombrowski R, Gereats DR, Amato MG. An economic analysis of a randomized controlled multi-center study of clinical pharmacist interventions for high-risk veterans: The IMPROVE Study. Pharmacotherapy 2000; 20(10):1149-1158.
Billups SJ, Malone DC, Carter BL. Economic outcomes of medication non-compliance. Pharmacotherapy 2000; 20(8):941-949.
MacLaughlin EJ, Saseen JJ, Malone DC. Selection and costs of antibiotics for patients with a reported beta-lactam allergy. Archives of Family Medicine 2000; 9:722-726.
Carter BC, Malone DC, Ellis SL, Dombrowski R. Antihypertensive drug utilization in hypertensive veterans with complex medication profiles. Journal of Clinical Hypertension 2000; 2: 172-180.
Ellis SA, Billups SJ, Malone DC, Carter BL, Covey D, Mason B, Jue S, Carmichael J, Guthrie K, Soloboda L, Sintek CD, Geraets DR, Dombrowski R, Amata M. Ambulatory care clinical pharmacist interventions: The IMPROVE Study. Pharmacotherapy 2000; 20(4):429-435.
Billups SJ, Okano GJ, Malone DC, Carter BL, Valuck RJ, Barnette DJ, Sintek CD. Assessing the structure and process for delivering pharmaceutical care in Veteran Affairs medical centers: The IMPROVE Study. American Journal of Health-System Pharmacy 2000; 57:29-39.
Malone DC, Rascati KL, Martin JD. An analysis of the product-liability costs borne by prescription drug manufacturers. Research in Finance 1999; 17:173-189.
Malone DC, Billups SJ, Valuck RJ, Carter BL. Development of a Chronic Disease Indicator Score Using a Veterans Affairs Medical Center Medication Database. Journal of Clinical Epidemiology 1999;52:551-557.
Malone DC, Okano GJ. Treatment of urge incontinence in Veterans Affairs medical centers. Clinical Therapeutics 1999;21:867-877.
Isaksen SF, Jonassen J, Malone DC, Billups SJ, Carter BL, Sintek CD. Estimating risk factors for patients with potential drug related problems using electronic pharmacy data. The Annals of Pharmacotherapy 1999; 33: 406-412.
Lousberg TR, Witt DM, Beall DG, Carter BL, Malone DC. Evaluation of excessive anticoagulation in a group model health maintenance organization. Archives of Internal Medicine 1998; 158: 528-534.
Malone DC, Lackner T, Korenblat BM, Babington M, Yoon P. A clinical and economic comparison of nifedipine CC and nifedipine GITS in long-term care patients. The Consultant Pharmacist 1998; 13(2): 182-192.
Alsuwaidan S, Malone DC, Billups SJ, Carter BL. Description of ambulatory care services provided by veterans affairs medical centers. American Journal of Health-System Pharmacy 1998; 55: 68-73.
Carter BL, Malone DC, Valuck R, Barnette DJ, Sintek C, Billups SJ. The IMPROVE Study: background and study design. American Journal of Health-System Pharmacy 1998; 55: 62-67.
Smith DH, Malone DC, Lawson KL, Okamoto LJ, Battista C, and Saunders WB. A national estimate of the economic costs of asthma. American Journal of Respiratory and Critical Care Medicine 1997; 156: 787-793.
Malone DC, Gwyn BC. Consultant pharmacist services and payment in long-term care facilities. The Consultant Pharmacist 1997; 12: 781-790.
Malone DC, Lawson KA, Smith DH, Arrighi HM, and Battista C. A Cost of illness study of allergic rhinitis in the United States. Journal of Allergy and Clinical Immunology 1997; 99: 22-27.
Malone DC, Rascati KL, Gagnon JP. Consumers' Evaluation of a Value-Added Pharmacy Services Program. American Pharmacy 1993; NS33(3): 48-56.