The streptomycete metabolite enterocin was recently isolated from tunicates in Australia. This finding is very suggestive of microbial participation within the invertebrate. In collaboration with Prof. Ron Quinn (Griffith University), we traveled to Queensland, Australia in the summer of 1999 and collected the enterocin-containing tunicate Aplidium lenticulum. With gene probes in hand from the cloning of the enc cluster from "Streptomyces maritimus", we have just started to study enterocin biosynthesis in the invertebrate as a model study for streptomycete-like metabolites in ascidians.